Publications

by the Rogers Lab

2024

• Ryniawec JM, Amoiroglou A, Rogers GC, "Generating CRISPR-edited clonal lines of cultured Drosophila S2 cells.", Biol Methods Protoc. 2024 Aug 17;9(1):bpae059. doi: 10.1093/biomethods/bpae059. PMID: 39206452.

2023

• Jensen CC, Clements AN, Liou H, Ball LE, Bethard JR, Langlais PR, Toth RK, Chauhan SS, Casillas AL, Daulat SR, Kraft AS, Cress AE, Miranti CK, Mouneimne G, Rogers GC, Warfel NA, "PIM1 phosphorylates ABI2 to enhance actin dynamics and promote tumor invasion.", J Cell Biol. 2023 Jun 5;222(6):e202208136. doi: 10.1083/jcb.202208136. Epub 2023 Apr 12.PMID: 37042842
• Ryniawec JM, Hannaford MR, Zibrat ME, Fagerstrom CJ, Galletta BJ, Aguirre SE, Guice BA, Dean SM, Rusan NM, Rogers GC, "Cep104 is a component of the centriole distal tip complex that regulates centriole growth and contributes to Drosophila spermiogenesis.", Curr Biol. 2023 doi: 10.1016/j.cub.2023.08.075.PMID: 37729913
• JM Ryniawec, DW Buster, LK Slevin, CJ Boese, A. Amoiroglou, SM Dean, KC Slep, GC Rogers, "Polo-like kinase 4 homodimerization and condensate formation regulate its own protein levels but are not required for centriole assembly.", Mol Biol Cell. 2023 Jul 1;34(8):ar80. doi: 10.1091/mbc.E22-12-0572. Epub 2023 May 10. PMID: 37163316
• Tingting Duan, Srikantha Thyagarajan, Anastasia Amoiroglou, Gregory C. Rogers, Pamela K. Geyer, "Analysis of a rare progeria variant of Barrier-to-autointegration factor in Drosophila connects centromere function to tissue homeostasis.", Cell Mol Life Sci. 80(3):73. doi: 10.1007/s00018-023-04721-y. 2023 Feb 26. PMID: 36842139

2022

• John M. Ryniawec, Matthew R. Coope, Emily Loertscher, Vignesh Bageerathan, Diogo de Oliveira Pessoa, Noel A. Warfel, Anne E. Cress, Megha Padi, Gregory C. Rogers, "GLUT3/SLC2A3 Is an Endogenous Marker of Hypoxia in Prostate Cancer Cell Lines and Patient-Derived Xenograft Tumors.", Diagnostics 12(3):676-696. doi: 10.3390/diagnostics12030676. 2022 Mar 10. PMID: 35328229
• John M. Ryniawec, and G. C. Rogers, "Balancing the scales: fine-tuning Polo-like kinase 4 to ensure proper centriole duplication.", Genes Dev. 36(11-12):647-649. doi: 10.1101/gad.349815.122. 2022 Jun 1. PMID: 35835509

2021

• John M. Ryniawec, and G. C. Rogers, "Centrosome instability: when good centrosomes go bad.", Cell Mol Life Sci. 78(21-22):6775-6795. doi: 10.1007/s00018-021-03928-1. 2021 Sep 2. PMID: 34476544

2020

• D. Mahadevan, and G. C. Rogers, "Janus Face of Drug-Induced Tetraploidy in Non-Hodgkin Lymphoma.", Trends Cancer. pii: S2405-8033(20)30118-7. doi: 10.1016/j.trecan.2020.03.009. 2020 Apr 11. PMID: 32291237
• McLamarrah, T. A., S. K. Speed, J. M. Ryniawec, D. W. Buster, C. J. Fagerstrom, B. J. Galletta, N. M. Rusan, and G. C. Rogers, "A molecular mechanism for the procentriole recruitment of Ana2.", J Cell Biol, vol. 219, issue 2, 2020 Feb 03. PMID: 31841145

2019

• Patrón, L. A., K. Nagatomo, D. Tyler Eves, M. Imad, K. Young, M. Torvund, X. Guo, G. C. Rogers, and K. E. Zinsmaier, "Cul4 ubiquitin ligase cofactor DCAF12 promotes neurotransmitter release and homeostatic plasticity.", J Cell Biol, 2019 Jan 22. PMID: 30670470
• Wang, M., B. S. Knudsen, R. B. Nagle, G. C. Rogers, and A. E. Cress, "A method of quantifying centrosomes at the single-cell level in human normal and cancer tissue.", Mol Biol Cell, vol. 30, issue 7, pp. 811-819, 2019 03 21. PMID: 30699045
  
• Gambarotto, D., C. Pennetier, J. M. Ryniawec, D. W. Buster, D. Gogendeau, A. Goupil, M. Nano, A. Simon, D. Blanc, V. Racine, Y. Kimata, G. C. Rogers, R. Basto, "Plk4 Regulates Centriole Asymmetry and Spindle Orientation in Neural Stem Cells.", Dev Cell, vol. 50, issue 1, pp. 11-24.e10, 2019 Jul 01. PMID: 31130353
• Wang, M., R. B. Nagle, B. S. Knudsen, A. E. Cress, and G. C. Rogers, "Centrosome loss results in an unstable genome and malignant prostate tumors.", Oncogene, 2019 Sep 02. PMID: 31477840

2018

• McLamarrah, T. A., D. W. Buster, B. J. Galletta, C. J. Boese, J. M. Ryniawec, N. Ann Hollingsworth, A. E. Byrnes, C. W. Brownlee, K. C. Slep, N. M. Rusan, et al., "An ordered pattern of Ana2 phosphorylation by Plk4 is required for centriole assembly.", J Cell Biol, vol. 217, issue 4, pp. 1217-1231, 2018 Apr 02. PMCID: PMC5881488  PMID: 29496738
• Xie, S., J. B. Reinecke, T. Farmer, K. Bahl, I. Yeow, B. J. Nichols, T. A. McLamarrah, N. Naslavsky, G. C. Rogers, and S. Caplan, "Vesicular trafficking plays a role in centriole disengagement and duplication.", Mol Biol Cell, vol. 29, issue 22, pp. 2622-2631, 2018 Nov 01. PMCID: PMC6249839  PMID: 30188792
• Boese, C. J., J. Nye, D. W. Buster, T. A. McLamarrah, A. E. Byrnes, K. C. Slep, N. M. Rusan, and G. C. Rogers, "Asterless is a Polo-like kinase 4 substrate that both activates and inhibits kinase activity depending on its phosphorylation state.", Mol Biol Cell, vol. 29, issue 23, pp. 2874-2886, 2018 Nov 15. PMCID: PMC6249866  PMID: 30256714

2017

• Wang, M., R. B. Nagle, B. S. Knudsen, G. C. Rogers, and A. E. Cress, "A basal cell defect promotes budding of prostatic intraepithelial neoplasia.", J Cell Sci, 01/2017. PMCID: PMC5394777  PMID: 27609833

2016

• Galletta, B. J., C. J. Fagerstrom, T. A. Schoborg, T. A. McLamarrah, J. M. Ryniawec, D. W. Buster, K. C. Slep, G. C. Rogers, and N. M. Rusan, "A centrosome interactome provides insight into organelle assembly and reveals a non-duplication role for Plk4.", Nat Commun, vol. 7, pp. 12476, 2016. PMID: 27558293

2015

• Klebba, J. E., D. W. Buster, T. A. McLamarrah, N. M. Rusan, and G. C. Rogers, "Autoinhibition and relief mechanism for Polo-like kinase 4.", Proc Natl Acad Sci U S A, vol. 112, issue 7, pp. E657-66, 2015 Feb 17. PMCID: PMC4343128  PMID: 25646492
• Wallace, H. A., J. E. Klebba, T. Kusch, G. C. Rogers, and G. Bosco, "Condensin II Regulates Interphase Chromatin Organization Through the Mrg-Binding Motif of Cap-H2.", G3 (Bethesda), vol. 5, issue 5, pp. 803-17, 2015 May. PMCID: PMC4426367  PMID: 25758823
• Nguyen, H. Q., J. Nye, D. W. Buster, J. E. Klebba, G. C. Rogers, and G. Bosco, "Drosophila casein kinase I alpha regulates homolog pairing and genome organization by modulating condensin II subunit Cap-H2 levels.", PLoS Genet, vol. 11, issue 2, pp. e1005014, 2015. PMCID: PMC4344196  PMID: 25723539
• Klebba, J. E., B. J. Galletta, J. Nye, K. M. Plevock, D. W. Buster, N. A. Hollingsworth, K. C. Slep, N. M. Rusan, and G. C. Rogers, "Two Polo-like kinase 4 binding domains in Asterless perform distinct roles in regulating kinase stability.", J Cell Biol, vol. 208, issue 4, pp. 401-14, 2015 Feb 16. PMCID: PMC4332252  PMID: 25688134
• Bozler, J., H. Q. Nguyen, G. C. Rogers, and G. Bosco, "Condensins exert force on chromatin-nuclear envelope tethers to mediate nucleoplasmic reticulum formation in Drosophila melanogaster.", G3 (Bethesda), vol. 5, issue 3, pp. 341-52, 2015 Mar. PMCID: PMC4349088  PMID: 25552604

2014

• Skwarek, L. C., S. L. Windler, G. de Vreede, G. C. Rogers, and D. Bilder, "The F-box protein Slmb restricts the activity of aPKC to polarize epithelial cells.", Development, vol. 141, issue 15, pp. 2978-83, 2014 Aug. PMCID: PMC4197664  PMID: 25053431
• Galletta, B. J., R. X. Guillen, C. J. Fagerstrom, C. W. Brownlee, D. A. Lerit, T. L. Megraw, G. C. Rogers, and N. M. Rusan, "Drosophila pericentrin requires interaction with calmodulin for its function at centrosomes and neuronal basal bodies but not at sperm basal bodies.", Mol Biol Cell, vol. 25, issue 18, pp. 2682-94, 2014 Sep 15. PMCID: PMC4161505  PMID: 25031429
• Nye, J., D. W. Buster, and G. C. Rogers, "The use of cultured Drosophila cells for studying the microtubule cytoskeleton.", Methods Mol Biol, vol. 1136, pp. 81-101, 2014. PMID: 24633795

2013

• Buster, D. W., S. G. Daniel, H. Q. Nguyen, S. L. Windler, L. C. Skwarek, M. Peterson, M. Roberts, J. H. Meserve, T. Hartl, J. E. Klebba, et al., "SCFSlimb ubiquitin ligase suppresses condensin II-mediated nuclear reorganization by degrading Cap-H2.", J Cell Biol, vol. 201, issue 1, pp. 49-63, 2013 Apr 1. PMCID: PMC3613687  PMID: 23530065
• Klebba, J. E., D. W. Buster, A. L. Nguyen, S. Swatkoski, M. Gucek, N. M. Rusan, and G. C. Rogers, "Polo-like kinase 4 autodestructs by generating its Slimb-binding phosphodegron.", Curr Biol, vol. 23, issue 22, pp. 2255-61, 2013 Nov 18. PMCID: PMC3844517  PMID: 24184097
• Smith, H. F., M. A. Roberts, H. Q. Nguyen, M. Peterson, T. A. Hartl, X-J. Wang, J. E. Klebba, G. C. Rogers, and G. Bosco, "Maintenance of interphase chromosome compaction and homolog pairing in Drosophila is regulated by the condensin cap-h2 and its partner Mrg15.", Genetics, vol. 195, issue 1, pp. 127-46, 2013 Sep. PMCID: PMC3761296  PMID: 23821596
• Brownlee, C. W., and G. C. Rogers, "Show me your license, please: deregulation of centriole duplication mechanisms that promote amplification.", Cell Mol Life Sci, vol. 70, issue 6, pp. 1021-34, 2013 Mar. PMID: 22892665

2012

• Mennella, V., B. Keszthelyi, K. L. McDonald, B. Chhun, F. Kan, G. C. Rogers, B. Huang, and D. A. Agard, "Subdiffraction-resolution fluorescence microscopy reveals a domain of the centrosome critical for pericentriolar material organization.", Nat Cell Biol, vol. 14, issue 11, pp. 1159-68, 2012 Nov. PMCID: PMC3767400  PMID: 23086239
• Slevin, L. K., J. Nye, D. C. Pinkerton, D. W. Buster, G. C. Rogers, and K. C. Slep, "The structure of the plk4 cryptic polo box reveals two tandem polo boxes required for centriole duplication.", Structure, vol. 20, issue 11, pp. 1905-17, 2012 Nov 7. PMCID: PMC3496063  PMID: 23000383
• Roberts, D. M., M. I. Pronobis, K. M. Alexandre, G. C. Rogers, J. S. Poulton, D. E. Schneider, K-C. Jung, D. J. McKay, and M. Peifer, "Defining components of the ß-catenin destruction complex and exploring its regulation and mechanisms of action during development.", PLoS One, vol. 7, issue 2, pp. e31284, 2012. PMCID: PMC3281067  PMID: 22359584

2011

• Brownlee, C. W., J. E. Klebba, D. W. Buster, and G. C. Rogers, "The Protein Phosphatase 2A regulatory subunit Twins stabilizes Plk4 to induce centriole amplification.", J Cell Biol, vol. 195, issue 2, pp. 231-43, 2011 Oct 17. PMCID: PMC3198173  PMID: 21987638

2010

• Rogers, G. C., "Spindle assembly: more than just microtubules.", Curr Biol, vol. 20, issue 8, pp. R364-6, 2010 Apr 27. PMID: 21749958
• Taylor, S. M., K. R. Nevis, H. L. Park, G. C. Rogers, S. L. Rogers, J. G. Cook, and V. L. Bautch, "Angiogenic factor signaling regulates centrosome duplication in endothelial cells of developing blood vessels.", Blood, vol. 116, issue 16, pp. 3108-17, 2010 Oct 21. PMCID: PMC2974614  PMID: 20664058
• Buster, D. W., J. Nye, J. E. Klebba, and G. C. Rogers, "Preparation of Drosophila S2 cells for light microscopy.", J Vis Exp, issue 40, 2010. PMCID: PMC3153891  PMID: 20543772

2009

• Rath, U., G. C. Rogers, D. Tan, M. Ana Gomez-Ferreria, D. W. Buster, H. J. Sosa, and D. J. Sharp, "The Drosophila kinesin-13, KLP59D, impacts Pacman- and Flux-based chromosome movement.", Mol Biol Cell, vol. 20, issue 22, pp. 4696-705, 2009 Nov. PMCID: PMC2777100  PMID: 19793918
• Rusan, N. M., and G. C. Rogers, "Centrosome function: sometimes less is more.", Traffic, vol. 10, issue 5, pp. 472-81, 2009 May. PMID: 19192251
• Rogers, G. C., N. M. Rusan, D. M. Roberts, M. Peifer, and S. L. Rogers, "The SCF Slimb ubiquitin ligase regulates Plk4/Sak levels to block centriole reduplication.", J Cell Biol, vol. 184, issue 2, pp. 225-39, 2009 Jan 26. PMCID: PMC2654306  PMID: 19171756

2008

• Hall, J. R., H. O. Lee, B. D. Bunker, E. S. Dorn, G. C. Rogers, R. J. Duronio, and J. Gowen Cook, "Cdt1 and Cdc6 are destabilized by rereplication-induced DNA damage.", J Biol Chem, vol. 283, issue 37, pp. 25356-63, 2008 Sep 12. PMCID: PMC2533066  PMID: 18617514
• Rogers, G. C., N. M. Rusan, M. Peifer, and S. L. Rogers, "A multicomponent assembly pathway contributes to the formation of acentrosomal microtubule arrays in interphase Drosophila cells.", Mol Biol Cell, vol. 19, issue 7, pp. 3163-78, 2008 Jul. PMCID: PMC2441692  PMID: 18463166
• Rogers, S. L., and G. C. Rogers, "Culture of Drosophila S2 cells and their use for RNAi-mediated loss-of-function studies and immunofluorescence microscopy.", Nat Protoc, vol. 3, issue 4, pp. 606-11, 2008. PMID: 18388942

2007

• Zhang, D., G. C. Rogers, D. W. Buster, and D. J. Sharp, "Three microtubule severing enzymes contribute to the "Pacman-flux" machinery that moves chromosomes.", J Cell Biol, vol. 177, issue 2, pp. 231-42, 2007 Apr 23. PMCID: PMC2064132  PMID: 17452528
• Kim, H., S-C. Ling, G. C. Rogers, C. Kural, P. R. Selvin, S. L. Rogers, and V. I. Gelfand, "Microtubule binding by dynactin is required for microtubule organization but not cargo transport.", J Cell Biol, vol. 176, issue 5, pp. 641-51, 2007 Feb 26. PMCID: PMC2064022  PMID: 17325206

2005

• Rogers, G. C., S. L. Rogers, and D. J. Sharp, "Spindle microtubules in flux.", J Cell Sci, vol. 118, issue Pt 6, pp. 1105-16, 2005 Mar 15. PMID: 15764594
• Mennella, V., G. C. Rogers, S. L. Rogers, D. W. Buster, R. D. Vale, and D. J. Sharp, "Functionally distinct kinesin-13 family members cooperate to regulate microtubule dynamics during interphase.", Nat Cell Biol, vol. 7, issue 3, pp. 235-45, 2005 Mar. PMID: 15723056

2004

• Kwon, M., S. Morales-Mulia, I. Brust-Mascher, G. C. Rogers, D. J. Sharp, and J. M. Scholey, "The chromokinesin, KLP3A, dives mitotic spindle pole separation during prometaphase and anaphase and facilitates chromatid motility.", Mol Biol Cell, vol. 15, issue 1, pp. 219-33, 2004 Jan. PMCID: PMC307542  PMID: 14528012
• Rogers, G. C., S. L. Rogers, T. A. Schwimmer, S. C. Ems-McClung, C. E. Walczak, R. D. Vale, J. M. Scholey, and D. J. Sharp, "Two mitotic kinesins cooperate to drive sister chromatid separation during anaphase.", Nature, vol. 427, issue 6972, pp. 364-70, 2004 Jan 22. PMID: 14681690
• Sharp, D. J., and G. C. Rogers, "A Kin I-dependent Pacman-flux mechanism for anaphase A.", Cell Cycle, vol. 3, issue 6, pp. 707-10, 2004 Jun. PMID: 15153812

2002

• Rogers, S. L., G. C. Rogers, D. J. Sharp, and R. D. Vale, "Drosophila EB1 is important for proper assembly, dynamics, and positioning of the mitotic spindle.", J Cell Biol, vol. 158, issue 5, pp. 873-84, 2002 Sep 2. PMCID: PMC2173155  PMID: 12213835

2001

• Scholey, J. M., G. C. Rogers, and D. J. Sharp, "Mitosis, microtubules, and the matrix.", J Cell Biol, vol. 154, issue 2, pp. 261-6, 2001 Jul 23. PMCID: PMC2150769  PMID: 11470815

2000

• Sharp, D. J., G. C. Rogers, and J. M. Scholey, "Cytoplasmic dynein is required for poleward chromosome movement during mitosis in Drosophila embryos.", Nat Cell Biol, vol. 2, issue 12, pp. 922-30, 2000 Dec. PMID: 11146657
  Chui, K. K., G. C. Rogers, A. M. Kashina, K. P. Wedaman, D. J. Sharp, D. T. Nguyen, F. Wilt, and J. M. Scholey, "Roles of two homotetrameric kinesins in sea urchin embryonic cell division.", J Biol Chem, vol. 275, issue 48, pp. 38005-11, 2000 Dec 1. PMID: 11006281
• Sharp, D. J., G. C. Rogers, and J. M. Scholey, "Microtubule motors in mitosis.", Nature, vol. 407, issue 6800, pp. 41-7, 2000 Sep 7. PMID: 10993066
• Rogers, G. C., K. K. Chui, E. W. Lee, K. P. Wedaman, D. J. Sharp, G. Holland, R. L. Morris, and J. M. Scholey, "A kinesin-related protein, KRP(180), positions prometaphase spindle poles during early sea urchin embryonic cell division.", J Cell Biol, vol. 150, issue 3, pp. 499-512, 2000 Aug 7. PMCID: PMC2175202  PMID: 10931863
• Sharp, D. J., G. C. Rogers, and J. M. Scholey, "Roles of motor proteins in building microtubule-based structures: a basic principle of cellular design.", Biochim Biophys Acta, vol. 1496, issue 1, pp. 128-41, 2000 Mar 17. PMID: 10722882
  Sharp, D. J., H. M. Brown, M. Kwon, G. C. Rogers, G. Holland, and J. M. Scholey, "Functional coordination of three mitotic motors in Drosophila embryos.", Mol Biol Cell, vol. 11, issue 1, pp. 241-53, 2000 Jan. PMCID: PMC14771  PMID: 10637305

1999

• Rogers, G.C., Hart, C.L., Wedaman, K.P., and J.M. Scholey, "Identification of kinesin-C, a calmodulin-binding carboxy-terminal kinesin in animal (Strongylocentrotus purpuratus) cells.", J Mol Biol, vol. 294, issue 19, pp. 1-8, 1999 Nov. PMID: 10556023

1997

• Kashina, A.S., Rogers, G.C., and J.M. Scholey, "The bimC family of kinesins: essential biopolar mitotic motors driving centrosome separation.", Biochim Biophys Acta, vol. 1357, issue 24, pp. 257-271, 1997 Jul. PMID: 9268050